BIOCHEMISTRY

topics: Location, rate limiting enzymes of all pathways Glycolysis and the different energetics Mitochondrial DNA: Properties and diseases Lesch Nyhan Syndrome & hyperuricemia, with causes Nucleotide chemistry, sources of atoms in rings PCR tRNA Vit. B1,B2 & B3 cofactors, coenzymes list, metabolic syndromes, storage disorders Amino acids-chemistry, metabolism & disorders (urea cycle-v.v. imp) Structure of proteins, seperatorytech of proteins (AIIMS & PGI mainly) Collagen structure, synthesis & disorder. Protein folding & degradation (PGI & AIIMS) Immuno globins Mechanism of enzyme action (Michealisconstant), enzyme inb., isoenzymes, enzymes as markers of organelle & membranes Carbohydrates-MPS, glucose transporters, metabolism Lipids - sphingolipidoses& metabolism Fuels of different organs in fed and fasting Lipoproteins & dyslipoproteinemia Genetics Vitamins - deficiency states with functions Porphyrias with heme synthesis with Hb structure Metabolism of Alcohol Enzyme inhibition, types and their Lineweaver Burk plot or double reciprocal plot Pharmacology